Antiplatelet Aggregation Plants

Medicinal Plants with Antiplatelet Activity

From this review, it was suggested that medicinal plants with antiplatelet activity mainly belong to the family of Asteraceae, Rutaceae, Fabaceae, Lamiaceae, Zygophyllaceae, Rhamnaceae, Liliaceae, and Zingiberaceae. The antiplatelet effect is attributed to the presence of bioactive compounds such as polyphenols, flavonoids, coumarins, terpenoids, and other substances which correct platelet …

Antiplatelet agents isolated from medicinal plants

In cooperation with chemists using bioassay-based step-by-step purification, some antiplatelet agents were isolated from plant sources. According to their effects on platelet aggregation, release reaction and signal transductions involved, these antiplatelet agents can be classified into eight groups: 1. platelet-activating factor (PAF) antagonists, 2. collagen-receptor antagonists, 3. thromboxane-receptor antagonists, 4. ADP-receptor agonists, 5. inhibitors of phosphoinositide breakdown, 6 ...

Comparative study of Antiplatelet Aggregation Activity of ...

Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of anti-inflammatory drugs because of their natural origin. The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical

Antiplatelet aggregating activity of extracts of ...

Request PDF | Antiplatelet aggregating activity of extracts of Indonesian medicinal plants I | Eight Indonesian medicinal plants (Cassia alata L., Cyclea barbata Miers, Imperata cylindrica (L ...

Antiplatelet aggregation activity of diterpene alkaloids ...

02/08/2002· Six diterpene alkaloids with an atisine-type C(20)-skeleton isolated from the Chinese herbal medicines Spiraea japonica var. acuta and S. japonica var. ovalifolia, as well as eight derivatives of spiramine C and spiradine F were evaluated for the ability to inhibit aggregation of rabbit platelets induced by arachidonic acid, ADP, and platelet-activating factor (PAF) in vitro. The results showed …

Coumarins and antiplatelet aggregation constituents from ...

01/02/1996· Studies searching for antiplatelet aggregation principles from Formosan plants revealed that the methanol extract of the root of this plant, collected in Lanyu Island, exhibited strong inhibitory activity on platelet aggregation in vitro.

Antiplatelet aggregation and antithrombotic benefits of ...

Accordingly, monoterpenoids are suggested as the main anti-platelet aggregation constituents from hawthorn leaves. Particularly, compounds 10 and 24 inhibited ADP-induced platelet aggregation and delayed FeCl3-induced thrombus in zebrafish. Furthermore, interactions between compounds 10 and 24 with two ADP receptors P2Y1 and P2Y12, serving as the target for key regulators of antiplatelet …

Coumarins and antiplatelet aggregation constituents from ...

Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum. Chen IS(1), Chang CT, Sheen WS, Teng CM, Tsai IL, Duh CY, Ko FN. Author information: (1)Graduate Institute of Pharmaceutical Sciences, Kaohsiung Medical College, Taiwan, ROC.

Cytotoxic and Antiplatelet Aggregation Principles of Ruta ...

Among them, dictamine (5), skimmianine (7), psoralen (8), chalepensin (12), clausindin (13), and graveolinine (16) showed significant inhibition of platelet aggregation, induced by …

Anti-platelet aggregation constituents from Gynura elliptica.

Anti-platelet aggregation constituents from Gynura elliptica. Lin WY(1), Teng CM, Tsai IL, Chen IS. Author information: (1)Graduate Institute of Pharmaceutical Sciences, Kaohsiung Medical College, Taiwan. A p-hydroxyacetophenone-like derivative, (+)-gynunone, and a chromane, together with six known compounds were isolated from the CHCl3 fraction of the roots of Gynura elliptica. Their ...

Coumarins and antiplatelet aggregation constituents …

01/02/1996· Studies searching for antiplatelet aggregation principles from Formosan plants revealed that the methanol extract of the root of this plant, collected in Lanyu Island, exhibited strong inhibitory activity on platelet aggregation in vitro. Examination of the chloroform-soluble part led to the isolation of four new khellactones esters (1--4) and 17 compounds known as isoimperatorin (5) [13], psoralen (6) [131, …

antiplatelet aggregation plants - Help4Help

Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of antiinflammatory drugs because of their natural origin. The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical

Antiplatelet aggregating activity of extracts of ...

Request PDF | Antiplatelet aggregating activity of extracts of Indonesian medicinal plants I | Eight Indonesian medicinal plants (Cassia alata L., Cyclea barbata Miers, Imperata cylindrica (L ...

Coumarins and antiplatelet aggregation constituents …

Among the isolates, seven compounds, eugenin, (-)-selinidin, (+)-pteryxin, imperatorin, bergapten, cnidilin and (+)-visamminol, show strong antiplatelet aggregation activity in vitro. PMID: 8821432

Anti-platelet aggregation constituents from Gynura …

Their structures were determined by means of spectral analyses. Among the isolates, 6-acetyl-2,2-dimethylchroman-4-one and vanillin showed anti-platelet aggregation activity induced by arachidonic acid in vitro. PMID: 10820787 [Indexed for MEDLINE] Publication Types: Research Support, Non-U.S. Gov't; MeSH terms. Acetophenones/chemistry

Anti-inflammatory, Antiplatelet Aggregation, and ...

In this study, we identified the active components with antiplatelet aggregation and antiangiogenesis activities, which may be related to the hemorrhagic disorder caused by this fungus. Moreover, we proposed a biosynthetic pathway of the isolated polyketide secondary metabolites and investigated their structure–activity relationship (SAR). Our results suggested that E. sorghinum is a potent source of …

Cytotoxic and Antiplatelet Aggregation Principles of …

Their antiplatelet aggregation and cytotoxic activities were examined to find potent antiplatelet aggregation and cytotoxic compounds from natural resources. Among them, dictamine ( 5 ), skimmianine ( 7 ), psoralen ( 8 ), chalepensin ( 12 ), clausindin ( 13 ), and graveolinine ( 16 ) showed significant inhibition of platelet aggregation, induced by arachidonic acid and collagen.

Antiplatelet aggregation activity of diterpene alkaloids ...

02/08/2002· 3.3.. Comparison of in vitro antiplatelet activities of atisine-type alkaloids with those of ginkgolide B and aspirinA comparison of the inhibitory effects of atisine-type alkaloids, ginkgolide B and aspirin on PAF, arachidonic acid and ADP-induced platelet aggregation is shown in Table 1.Of the 14 test compounds, 12 selectively inhibited platelet aggregation induced by PAF.

Medicinal Plants with Antiplatelet Activity | Request PDF

From this review, it was suggested that medicinal plants with antiplatelet activity mainly belong to the family of Asteraceae, Rutaceae, Fabaceae, Lamiaceae, Zygophyllaceae, Rhamnaceae, Liliaceae,...

Alkaloids from Houttuynia cordata and Their Antiplatelet ...

01/11/2011· [KEY WORDS] Houttuynia cordata; Alkaloids; Antiplatelet aggregation activities [CLC Number] R284.1; R965 [Document code] A [Article ID] 1672-3651(2011)06-0425-04 1 Introduction Houttuynia cordata Thunb. (Saururuacea) is a traditional medicinal plant grown in East Asia. This plant has several pharmacological activities including antiviral, anti-inflamma- tory and immunostimulating …

antiplatelet aggregation plants - Help4Help

Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of antiinflammatory drugs because of their natural origin. The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical

Antiplatelet aggregating activity of extracts of ...

Request PDF | Antiplatelet aggregating activity of extracts of Indonesian medicinal plants I | Eight Indonesian medicinal plants (Cassia alata L., Cyclea barbata Miers, Imperata cylindrica (L ...

Anti-inflammatory, Antiplatelet Aggregation, and ...

active compounds that can be developed as antiplatelet aggregation and anti-inflammatory agents. INTRODUCTION Natural products from terrestrial plants, microbial organisms, and marine organisms played a key role in drug discovery and development throughout the last two centuries. Many current therapeutic drugs have their origins from natural products or

(PDF) Antiplatelet aggregation and cytotoxic activity of ...

Antiplatelet aggregation and cytotoxic activity of betulinic acid and its acetyl derivative from Melaleuca bracteata June 2015 Journal of Medicinal Plant Research 9(22):647-654

Data on antiplatelet aggregation, anticoagulation and ...

01/10/2020· The data presented in this article characterize the antiplatelet aggregation, anticoagulant and antioxidant activity of C. edulis rhizome extracts and the bio-guided isolation of bioactive compounds from the active fraction. The data on tested bioactivities of isolated compounds were also provided. The inhibitory effect on adenosine diphosphate- and collagen-induced human platelet aggregation was …

Antiplatelet aggregation activity of diterpene alkaloids ...

02/08/2002· 3.3.. Comparison of in vitro antiplatelet activities of atisine-type alkaloids with those of ginkgolide B and aspirinA comparison of the inhibitory effects of atisine-type alkaloids, ginkgolide B and aspirin on PAF, arachidonic acid and ADP-induced platelet aggregation is shown in Table 1.Of the 14 test compounds, 12 selectively inhibited platelet aggregation induced by PAF.

Medicinal Plants with Antiplatelet Activity | Request PDF

From this review, it was suggested that medicinal plants with antiplatelet activity mainly belong to the family of Asteraceae, Rutaceae, Fabaceae, Lamiaceae, Zygophyllaceae, Rhamnaceae, Liliaceae,...

Alkaloids from Houttuynia cordata and Their Antiplatelet ...

01/11/2011· [KEY WORDS] Houttuynia cordata; Alkaloids; Antiplatelet aggregation activities [CLC Number] R284.1; R965 [Document code] A [Article ID] 1672-3651(2011)06-0425-04 1 Introduction Houttuynia cordata Thunb. (Saururuacea) is a traditional medicinal plant grown in East Asia. This plant has several pharmacological activities including antiviral, anti-inflamma- tory and immunostimulating …

(PDF) In Vitro Antiplatelet Activity of Tridax procumbens ...

The anti-platelet aggregation activity of the leaf extracts of Saraca indica were assessed by the presence of aggregation free platelets, when extracts were incubated with calcium chloride ...

ANTIPLATELET AND ANTIHEMOLYTIC ACTIVITIES OF ...

ABSTRACT: This study designed to evaluate the antiplatelet and antihemolytic activity of hydroethanolic extract of Annona muricata leaves (HEEAM). The platelet aggregation assay was carried out using platelet-rich plasma, and the antihemolytic assay was done by hydrogen peroxide with different concentration of plant extract (100-500 μg/ml).

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